LANNATE(R) INSECTICIDE
Du Pont Agricultural Products
M0000060
Revised: 12-OCT-1996
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CHEMICAL PRODUCT/COMPANY IDENTIFICATION
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Material Identification
LANNATE is a registered trademark of DuPont.
Corporate MSDS Number: DU003803
Grade: A 90% FORMULATION
Tradenames and Synonyms: Lannate 90-WD; 90-WD
Company Identification
DU PONT
1007 Market Street
Wilmington, DE 19898
PHONE NUMBERS
Product Information:1-800-441-7515Transport Emergency:
CHEMTREC:1-800-424-9300Medical Emergency:1-800-441-3637
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COMPOSITION/INFORMATION ON INGREDIENTS
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Components
Material CAS Number %
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Methomyl 16752-77-5 90
(s-methyl-n-[(methylcarbamoyl)oxy]thio-
acetimidate)
Inert Ingredients 10
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HAZARDS IDENTIFICATION
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Potential Health Effects
DANGER! POISON! Fatal if swallowed. May be fatal if inhaled or absorbed
through eyes.
WARNING SYMPTOMS: Methomyl poisoning produces effects associated with
anticholinesterase activity which may include weakness, blurred vision,
headache, nausea, abdominal cramps, discomfort in the chest, constriction
of pupils, sweating, slow pulse, muscle tremors.
ANIMAL DATA
Acute Oral LD50: (Active ingredient, fasted rats) 17 mg/kg (males); 24
mg/kg (females).
Highly toxic by ingestion.
Acute Dermal LD50: (Active ingredient, aqueous slurry) > 5,000 mg/kg (male
rabbits; intact skin).
Slightly toxic by contact.
INHALATION
4 hour LC50: 0.30 mg/L (male albino rats). Toxic by inhalation.
SKIN IRRITATION AND SENSITIZATION (Guinea pigs): Application to shaved
skin as a 60% paste in propylene glycol, a 5% solution in propylene glycol
or in water, or as 24% or 29% liquid formulation resulted in mild to no
irritation and no sensitization.
EYE IRRITATION (Rabbit): Ten mg of unformulated Methomyl, either
as a powder or solution in propylene glycol, caused mild transient
conjunctivitis and iritic congestion on the day of treatment; no corneal
injury was observed. Excessive quantities of the unformulated powder were
lethal via ocular exposure. This exposure was within the equivalent range
that produced mortalities via oral administration.
Both unformulated Methomyl and various formulations caused pupillary
constriction and other effects associated with anticholinesterase activity.
CHRONIC STUDIES--METHOMYL
2-year feeding in rats: Feeding levels 0, 50, 100, 200, and 400 ppm; no
effect level (NOEL) of 100 ppm based on slight hemolytic anemia and/or body
weight effects observed at the higher dietary concentrations. No compound
related neoplastic lesions were observed.
2-year feeding in mice: Feeding levels 0, 50, 75, and 200 ppm; no compound
related neoplastic or non-neoplastic histologic effects were found at any
level. The NOEL was considered to be 50 ppm based on transient hemolytic
anemia and increased mortality at the higher dietary concentrations.
2-year feeding in dogs: Feeding levels 0, 50, 100, 400, and 1,000 ppm. The
NOEL of 100 ppm was based on hemolytic anemia and nonneoplastic changes
within the kidney and spleen at the higher dietary concentrations. There
were no neoplastic effects at any dose.
REPRODUCTION: Three-generation rat reproduction study at dietary rates of
50 and 100 ppm showed no adverse effect upon fertility, and no compound
related histologic effect. A 2-generation rat study conducted at 75, 600,
and 1,200 ppm in the diet showed similar results.
TERATOGENICITY: In rats, no embryotoxic or teratogenic effects were
observed at levels up to 400 ppm (highest level fed). In rabbits, the
highest dietary dose level (equivalent to 100 mg/kg body wt.) did not cause
any observed compound related abnormalities.
MUTAGENICITY: Methomyl was negative in numerous assays to evaluate
mutagenicity and genotoxicity, including Ames test, Reverse Mutation Assay,
Recessive Lethal Assay, three DNA damage studies, an unscheduled DNA
Synthesis Assay, and in vitro and in vivo cytogenetic assays.
ACCEPTABLE DAILY INTAKE: Based on the 100 ppm no-observable effect level
of the 2-year dog feeding study, and utilizing a 100 fold safety factor,
the U.S. EPA has established an Acceptable Daily Intake of 0.025 mg per
kilogram of body weight per day.
Carcinogenicity Information: None of the components present in this
material at concentrations equal to or greater than 0.1% are listed by
IARC, NTP, OSHA, or ACGIH as a carcinogen.
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FIRST AID MEASURES
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First Aid
This Product is an N-Methyl Carbamate insecticide.
IF SWALLOWED: Call a physician or Poison Control Center. Drink 1 or
2 glasses of water and induce vomiting by touching back of throat with
finger. Do not induce vomiting or give anything by mouth to an unconscious
person.
IF INHALED: Remove from exposure and have patient lie down and keep quiet.
If patient is not breathing, start artificial respiration immediately.
Never give anything by mouth to an unconscious person. Call a physician if
necessary.
IN CASE OF CONTACT: Wash skin with plenty of soap and water; for eyes,
flush with water for 15 minutes and get medical attention; remove and wash
contaminated clothing before reuse.
Notes to Physicians: Atropine sulfate should be used for treatment.
Administer repeated doses, 1.2 to 2.0 mg intravenously every 10 to 30
minutes until full atropinization is achieved. Maintain atropinization
until the patient recovers. Artificial respiration or oxygen may be
necessary. Allow no further exposure to any cholinesterase inhibitor until
recovery is assured.
Do not use 2-PAM for exposure to Lannate alone. However, for exposure to
combinations of Lannate and organophosphorous insecticides, 2-PAM may be
used as required to supplement the atropine sulfate treatment. Do not use
morphine.
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FIRE FIGHTING MEASURES
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Flammable Properties
Flammable limits in Air, % by Volume:
LEL: 0.096 g/L
Autodecomposition: 136C (277F)
Will ignite if exposed to intense heat or open flame.
Dust forms explosive mixture with air.
Fire and Explosion Hazards: Fire or intense heat may cause violent rupture
of packages. Heating can release vapors which can be ignited. Hazardous
gases produced in fire under conditions that produce incomplete combustion
may consist of SO2, NO2, CO2, HCN, CH3NCO, CO, CS2. Complete combustion
greatly reduces the amounts of CS2, CO, HCN, and CH3NCO generated.
Extinguishing Media: Water spray, water fog, dry chemical, CO2.
Fire Fighting Instructions: Evacuate personnel to a safe area. Keep
personnel removed and upwind of fire. Wear self-contained breathing
apparatus. Wear full protective equipment. Use water spray. Cool
tank/container with water spray. Isolate area. Fight fire from maximum
distance, use extreme caution as heat may decompose material and rupture
containers.
If area is heavily exposed to fire and if conditions permit, let fire burn
itself out since water may increase the area contaminated.
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ACCIDENTAL RELEASE MEASURES
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Safeguards (Personnel): NOTE: Review FIRE FIGHTING MEASURES and HANDLING
(PERSONNEL) sections before proceeding with cleanup. Use appropriate
PERSONAL PROTECTIVE EQUIPMENT during cleanup.
Initial Containment: Remove source of heat, sparks, flame, impact,
friction, or electricity.
Accidental Release Measures: Contain spill. Shovel or sweep up powder. Use
sawdust, sand, oil dry, or other absorbent material as an aid to removing
remaining traces of spilled material. Do not allow the material to enter
sewers, waterways, or low areas.
If product enters crevices and can not be removed, treat with a sodium
hydroxide solution, and allow to stand 4 hours.
NOTE: Sodium hydroxide is caustic and causes burns. Do not get in eyes, on
skin, or on clothing. In case of contact, flush eyes or skin with plenty of
water and call a physician. When handling, wear goggles in addition to
boots and gloves.
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HANDLING AND STORAGE
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Handling (Personnel): Do not breathe vapor or mist. Do not breathe dust. Do
not get in eyes, on skin, or on clothing. Wash thoroughly after handling.
Wash clothing after use. Do not store or consume food, drink, or tobacco in
areas where they may become contaminated with this material.
Users Should: Wash hands before eating, drinking, chewing gum, using
tobacco or using the toilet. Remove clothing immediately if pesticide gets
inside. Then wash thoroughly and put on clean clothing. Remove personal
protective equipment immediately after handling this product. Wash the
outside of gloves before removing.
Handling (Physical Aspects): Avoid dust generation. Keep away from heat,
sparks, and flames.
Storage: Handle this package carefully to prevent breakage of inner bag
when stored at low temperatures. Allow to warm above 50 deg F for normal
handling. Store product in original container only, away from other
pesticides, fertilizer, food, or feed in storage. Not for use or storage in
or around the home.
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EXPOSURE CONTROLS/PERSONAL PROTECTION
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Engineering Controls: Use only with adequate ventilation. Keep container
tightly closed.
Personal Protective Equipment
Applicators and other handlers must wear:
Long-sleeved shirt and long pants
Waterproof gloves
Shoes plus socks
Protective eyewear
For exposures in enclosed areas, a respirator with either an organic
vapor-removing cartridge with a prefilter approved for pesticides
(MSHA/NIOSH approval number prefix TC-23C), or a canister approved for
pesticides (MSHA/NIOSH approval number prefix TC-14G).
For exposures outdoors, a dust/mist filtering respirator (MSHA/NIOSH
approval number prefix TC-21C).
Discard clothing or other absorbent materials that have been drenched or
heavily contaminated with this product's concentrate. Do not reuse them.
Follow manufacturer's instructions for cleaning/maintaining PPE. If no such
instructions for washables, use detergent and hot water. Keep and wash PPE
separately from other laundry.
PPE required for early reentry to treated areas that is permitted under the
Worker Protection Standard and that involves contact with anything that has
been treated, such as plants, soil, or water, is:
Coveralls
Waterproof gloves
Shoes plus socks
Protective eyewear
# Exposure Guidelines
Applicable Exposure Limits
METHOMYL
PEL (OSHA): None established.
TLV (ACGIH): 2.5 mg/m^3, 8 Hr. TWA, A4
AEL * (Du Pont): None established.
* AEL is Du Pont's Acceptable Exposure Limit. Where governmentally imposed
occupational exposure limits which are lower than the AEL are in effect,
such limits shall take precedence.
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PHYSICAL AND CHEMICAL PROPERTIES
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Physical Data
Solubility in Water: 5.8 WT% @ 25C (77F)
Odor: Slightly sulfurous.
Form: Solid.
Color: White.
Specific Gravity: 1.2946 @ 25C (77F)
Bulk Density (Loose): 30-38 lb/cu ft
Bulk Density (Packed): 37-43 lb/cu ft
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STABILITY AND REACTIVITY
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Chemical Stability: Stable at normal temperatures and storage conditions.
Incompatibility with Other Materials: Incompatible with strong bases.
Polymerization: Polymerization will not occur.
Other Hazards: Decomposition: Thermal decomposition and combustion
will produce hazardous gases. These may include sulfur oxides, methyl
isocyanate, and hydrogen cyanide.
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ECOLOGICAL INFORMATION
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Ecotoxicological Information
Aquatic Toxicity
Methomyl is extremely toxic:
96 hour LC50, bluegill sunfish: 0.72 ppm
96 hour LC50, rainbow trout: 3.4 ppm
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DISPOSAL CONSIDERATIONS
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Waste Disposal: Treatment, storage, transportation, and disposal must
be in accordance with applicable Federal, State/Provincial, and local
regulations. Do not flush to surface water or sanitary sewer system.
DISPOSAL: Do not contaminate water, food, or feed by storage or disposal.
Pesticide wastes are acutely hazardous. Improper disposal of excess
pesticide, spray mixture, or rinsate is a violation of Federal law. If
these wastes cannot be disposed of by use according to label instructions,
contact your State Pesticide or Environmental Control Agency, or the
Hazardous Waste representative at the nearest EPA Regional Office for
guidance.
CONTAINER DISPOSAL: Completely empty bag into application equipment. Then
dispose of empty package in a sanitary landfill or by incineration, or, if
allowed by State and local authorities, by burning. If burned, stay out of
smoke.
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TRANSPORTATION INFORMATION
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Shipping Information
DOT/IMO
Proper Shipping Name: CARBAMATE PESTICIDE, SOLID, TOXIC (methomyl)
Hazard Class: 6.1
UN No.: UN 2757
Special Information: Marine Pollutant (water or bulk).
Packing Group: II
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REGULATORY INFORMATION
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U.S. Federal Regulations
TITLE III HAZARD CLASSIFICATIONS SECTIONS 311, 312
Acute: Yes.
Chronic: No.
Fire: No.
Reactivity: No.
Pressure: No.
ADDITIONAL REGULATORY INFORMATION
Section 302 Extremely Hazardous Substance:
Methomyl--Threshold Planning Quantity (TPQ)
(500/10,000 lbs).
SARA/CERCLA Reportable Quantity: Methomyl (100 lbs).
REGULATORY CONTROLS: This product is registered under EPA/FIFRA
regulations. It is a violation of Federal laws to use this product in
any manner inconsistent with its labeling. Read and follow all label
directions. This product is excluded from listing requirements under
EPA/TSCA.
EPA Reg. No.: 352-342
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OTHER INFORMATION
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NFPA, NPCA-HMIS
NFPA Rating
Health: 2
Flammability: 1
Reactivity: 1
NPCA-HMIS Rating
Health: 3
Flammability: 1
Reactivity: 1
Personal Protection rating to be supplied by user depending on use
conditions.
Additional Information: RESTRICTED USE PESTICIDE
Due to High Acute Toxicity to Humans.
For retail sale to and use only by Certified Applicators or persons under
their direct supervision and only for those uses covered by the Certified
Applicator's Certification.
Direct supervision for this product requires the Certified Applicator to
review Federal and supplemental label instructions with all personnel prior
to application, mixing, loading or cleaning of application equipment.
The data in this Material Safety Data Sheet relates only to the specific
material designated herein and does not relate to use in combination with
any other material or in any process.
Responsibility for MSDS: DuPont
Address: Agricultural Products
Wilmington, DE 19898
Telephone: 800-441-7515
# Indicates updated section.